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Anti -Fas Ligand Rabbit pAb

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貨號:
DRF101623
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
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Product Information


Description

Fas Ligand rabbit polyclonal

Protein full name

Tumor necrosis factor ligand superfamily member 6

Synonyms

ALPS1A, APO 1, Apo 1 antigen, APT1, CD95, FAS, FAS1, FASLG receptor, FASTM, TNFRSF6

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse FASL

Isotype IgG
Purity Affinity purification
Subcellular location

Cell membrane

Uniprot ID

P25445, P25446, Q63199




Applications


Applications Species Dilution Positive Tissue
IHC Human, Mouse, Rat 1: 500-1: 3000 Appendix, spleen,
Thymus, liver
IF Mouse, Rat 1: 1500-
1: 3000
small intestine, thymus, lung




Background



Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.




Images



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Immunohistochemistry analysis of paraffin-embedded human appendix  using FasL (GB11090-1) at dilution of 1:1000

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Immunohistochemistry analysis of paraffin-embedded mouse Immunized spleen using FasL (GB11090-1) at dilution of 1:1000

blob.png Immunohistochemistry analysis of paraffin-embedded mouse Immunized thymus using FasL (GB11090-1) at dilution of 1:1000
blob.png

Immunohistochemistry analysis of paraffin-embedded rat liver using FasL (GB11090-1) at dilution of 1:1000

blob.png

Immunohistochemistry analysis of paraffin-embedded rat spleen using FasL (GB11090-1) at dilution of 1:1000

Immunofluorescent analysis of paraformaldehyde-fixed mouse small intestine using FasL(GB11090-1) at dilution of 1: 1500

Immunofluorescent analysis of paraformaldehyde-fixed rat thymus using FasL(GB11090-1) at dilution of 1: 1500

Immunofluorescent analysis of paraformaldehyde-fixed rat lung using FasL(GB11090-1) at dilution of 1: 3000




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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