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Anti -LIFR Rabbit pAb

價格: 在線咨詢
貨號:
DRF101656
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購買數(shù)量:
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Product Information


Description

LIFR rabbit polyclonal

Protein full name

Leukemia inhibitory factor receptor

Synonyms

LIF receptor, LIF-R, D-factor/LIF receptor, CD118, Lifr, SJS2, STWS, LIF-R, LIFR

Immunogen

Recombinant protein corresponding to Mouse LIFR

Isotype

IgG

Purity

Affinity purification

Predicted MW.

123 kDa

Observed MW.

190 kDa

Uniprot ID

P42703, O70535




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

heart, liver, kidney, placenta




Background

LIFR, also known as CD118 is a subunit of a receptor for leukemia inhibitory factor (LIF). LIF is a pleiotropic cytokine of the interleukin-6 family which affects the differentiation, survival, and proliferation of a wide variety of cells in the adult and the embryo. LIFR is the low-affinity binding chain that, together with the high-affinity converter subunit gp130, forms a high-affinity receptor complex that mediates the action of LIF. The high-affinity complex also binds a related cytokine, oncostatin M. LIFR has also been identified as a breast cancer metastasis suppressor that functions through the HIPPO-YAP pathway.




Images



Western blot analysis of LIFR (GB111476)
at dilution of 1: 1000
Lane 1: Mouse heart tissue lysate
Lane 2: Mouse liver tissue lysate
Lane 3: Mouse kidney tissue lysate
Lane 4: Mouse placenta tissue lysate
Lane 5: Rat liver tissue lysate
Lane 6: Rat placenta tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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