Anti -Myelin Basic Protein Rabbit pAb

價格：在線咨詢

貨號：

KT011601

產(chǎn)品規(guī)格：

100 μL

Applications：

WB | IHC | IF

Species：

M,R/M,R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	Myelin Basic Protein rabbit polyclonal antibody
Protein full name	Myelin Basic Protein
Synonyms	MBP, entrez:4155, myelin basic protein
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse Myelin Basic Protein
Isotype	IgG
Purity	Affinity purification
Subcellular location	Myelin membrane, Cytoplasmic side of myelin
Predicted MW.	27 kDa
Observed MW.	17/20 kDa
Uniprot ID	P04370, P02688

Applications

Applications	Species	Dilution	Positive Sample
WB	Mouse, Rat	1:500-1:1000	brain
IHC/IF	Mouse, Rat	1:300-1:600	brain

Background

The classic group of MBP isoforms (isoform 4-isoform 13) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined to optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function.

Images

Western blot analysis of Myelin Basic Protein (GB11226) at dilution of 1: 500

Immunofluorescence of paraffin embedded mouse brain using MBP (GB11226) at dilution of 1: 300 (400x lens)

Immunofluorescence of paraffin embedded rat brain using MBP (GB11226) at dilution of 1: 300 (400x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.

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