Anti -Cyclin A1 Rabbit pAb

價格：在線咨詢

貨號：

KT011852

產(chǎn)品規(guī)格：

100 μL

Applications：

IHC/IF

Species：

M,R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	Cyclin A1 rabbit polyclonal antibody
Protein full name	Cyclin-A1
Synonyms	Ccna1, G2/mitotic specific cyclin A1
Immunogen	Recombinant protein corresponding to Mouse Cyclin A1
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cytoplasm, Nucleus
Uniprot ID	Q61456

Applications

Applications	Species	Dilution	Positive Sample
IHC/IF	Mouse, Rat	1: 400-1: 800	testis

Background

The critical role that the family of regulatory proteins known as cyclins play in eukaryotic cell cycle regulation is well established. The best-characterized cyclin complex is the mitotic cyclin B/Cdc2 p34 kinase, the active component of maturing promoting factor. Cyclin A accumulates prior to cyclin B in the cell cycle, appears to be involved in control of S phase and has been shown to associate with cyclin-dependent kinase-2 (Cdk2). In addition, cyclin A has been implicated in cell transformation and is found in complexes with E1A, transcription factors DRTF1 and E2F and retinoblastoma protein, p110. A second form of cyclin A, named cyclin A1 because of its high sequence homology to Xenopus cyclin A1, is most highly expressed in germ cells.

Images

Picture 1.png

Immunohistochemistry of paraffin embedded mouse testis using CCNA1 (GB111921) at dilution of 1:400 (300x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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