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Anti -SDHB Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
KT011930
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
MR
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information

Description

SDHB rabbit polyclonal antibody

Protein full name

Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

Synonyms

Iron-sulfur subunit of complex II, Ip, Sdhb, SDHIP, PGL4, SDH, SDH1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse SDHB

Isotype

IgG

Purity

Affinity purification

Predicted MW.

32 kDa

Observed MW.

28 kDa

Uniprot ID

Q9CQA3, P21913





Applications

Applications

Species

Dilution

Positive Sample

WB

Mouse, Rat

1: 500-1: 1000

brain, liver, kidney





Background

SDHB(Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial) is also named as SDH, SDH1 and belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. The SDHD, SDHB, and SDHC genes encode subunits of mitochondrial complex II (succinate dehydrogenase).Mitochondrial complex II is a heterotetrameric complex involved in the aerobic electron transport chain and catalyses the oxidation of succinate to fumarate (Krebs cycle) with transport of electrons to the ubiquinone pool. SDHA and SDHB are the hydrophilic catalytic part of the complex and are highly conserved. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.





Images

Picture 1.png


Western blot analysis of SDHB (GB111344) at dilution of 1: 500





Storage

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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