Anti -CBX2 Rabbit pAb

價格：在線咨詢

貨號：

KT012194

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

HMR

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	CBX2 rabbit polyclonal antibody
Protein full name	Chromobox protein homolog 2
Synonyms	M33, Modifier 3 protein, Cbx2, CDCA6, MOD2, SRXY5, Polycomb
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse CBX2
Isotype	IgG
Purity	Affinity purification
Predicted MW.	55 kDa
Observed MW.	55 kDa
Uniprot ID	Q14781, P30658

Applications

Applications	Species	Dilution	Positive Sample
WB	Human, Mouse, Rat	1: 500-1: 1000	liver, spleen, testis

Background

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development . PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility . Binds to histone H3 trimethylated at 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3) . Plays a role in the lineage differentiation of the germ layers in embryonic development . Involved in sexual development, acting as activator of NR5A1 expression .

Images

Picture 1.png

Western blot analysis of CBX2 (GB112013) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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