Anti -IKB alpha Rabbit pAb

價格：在線咨詢

貨號：

KT012220

產品規(guī)格：

Applications：

IHC/IF

Species：

H/H

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產品詳情操作說明注意事項

Product Information

Description	IKB alpha rabbit polyclonal
Protein full name	NF-kappa-B inhibitor alpha
Synonyms	NFKBIA, IKBA, MAD-3, NFKBI, NFKB inhibitor alpha
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse IKBα
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cytoplasm, Nucleus
Uniprot ID	P25963, Q9Z1E3

Applications

Applications	Species	Dilution	Positive Tissue
IHC	Human	1: 500-1: 3000	lung cancer, liver cancer, stomach cancer
IF	Human	1: 500-1: 1000	lung cancer, liver cancer, stomach cancer

Background

Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.

Images

Immunohistochemistry analysis of paraffin-embedded human lung cancer using IKBα (GB11212) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded human colon cancer using IKBα (GB11212) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded human stomach cancer using IKBα (GB11212) at dilution of 1: 1000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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