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Anti -Phospho-ERK1 (T202/Y204) + ERK2 (T185/Y187) Rabbit pAb

價格: 在線咨詢
貨號:
KT012252
產(chǎn)品規(guī)格:
100ul
Applications:
WB
Species:
M/R
購買數(shù)量:
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Product Information


Description

Phospho-ERK1 (T202/Y204) + ERK2 (T185/Y187) rabbit polyclonal antibody

Protein full name

Mitogen-activated protein kinase 1

Synonyms

APK1, ERK, ERK-1, ERK-2, ERK1, ERK2, ERT1, MAPK1,MAPK3, P42MAPK, P44MAPK, PRKM1, PRKM2, p44, p42, p44-MAPK, p42-MAPK, P-ERK, P-ERK1/2, P-ERK1, P-ERK2

Immunogen

KLH conjugated Synthetic phosphopeptide corresponding to Human ERK1 (T202/Y204) + ERK2 (T185/Y187)

Isotype

IgG

Purity

Affinity purification

Predicted MW.

41 kDa

Observed MW.

43 kDa

Uniprot ID

P63085, P63086


Applications


Applications

Species

Dilution

Positive Sample

WB

Mouse, Rat

1: 400-1: 800

lung, kidney


Background



Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.




Images



Picture 1.png

Western blot analysis of ERK1 (T202/Y204) + ERK2 (T185/Y187)  at dilution of 1: 800




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100μg/ml BSA and 50% glycerol.




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